alexa Autologous Transplantation of Cryopreserved Ovarian Tis
ISSN: 1948-5956

Journal of Cancer Science & Therapy
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Case Report

Autologous Transplantation of Cryopreserved Ovarian Tissue to the Upper Extremity for the Preservation of Ovarian Function in Young Patient with Cervical Carcinoma

Chen Meiyi1, Shao Yin1*, Ma Liguo1, Zhuang Yongqing2, and Wang Xiaomei3

1Department of Gynecology, Shenzhen People’s Hospital, Second Affiliated Hospital of Jinan University, Shenzhen, P. R. China

2Department of Microsurgery, Shenzhen People’s Hospital, Second Affiliated Hospital of Jinan University, Shenzhen, P. R. China

3The Engineering Lab of Synthetic Biology and the Key Lab of Biomedical Engineering, School of Medicine, Shenzhen University, Shenzhen, P. R. China

*Corresponding Author:
Shao Yin
M.D, Department of Gynecology, Shenzhen
People’s Hospital, Second Affiliated Hospital
of Jinan University No. 1017, Dong Min Bei Lu
Shenzhen, 518060, P. R. China
Tel: 075522948600
E-mail: [email protected]

Received date: March 28, 2017; Accepted date: April 10, 2017; Published date: April 17, 2017

Citation: Meiyi C, Yin S, Liguo M, Yongqing Z, Xiaomei W (2017) Autologous Transplantation of Cryopreserved Ovarian Tissue to the Upper Extremity for the Preservation of Ovarian Function in Young Patient with Cervical Carcinoma. J Cancer Sci Ther 9:401-404. doi: 10.4172/1948-5956.1000449

Copyright: © 2017 Meiyi C, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

For women of reproductive age with cervical carcinoma, they usually receive not only standard surgical treatment but also postoperative radiotherapy to increase the cure rates. However, infertility and premature ovarian failure are often occurred after radiotherapy. Autotransplantation of cryopreserved ovarian tissue is a new technique for preserving gonadal function for cervical cancer patients of reproductive age. Here, a successful ovarian function recovery through cryopreservation and autotransplantation in a case of 28-year-old patient with cervical cancer was reported. In brief, a slow-programmed freezing/thawing method was conducted for ovarian cortex cryopreservation. Six thawed ovarian cortical slices were transplanted to the left upper arm after the radiotherapy. The ovarian endocrine functions and follicle growth was successfully improved to normal level at 12 months after autotransplantation. In conclusion, autotransplantation of cryopreserved ovarian cortex for ovarian function preservation is a viable option for cervical cancer patients to gain the quality of life and avoid the suffering from conventional menopause hormone therapy.

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