alexa Automatized Procedure to Shape a Regional Personalized
ISSN: 2155-9538

Journal of Bioengineering & Biomedical Science
Open Access

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Short Communication

Automatized Procedure to Shape a Regional Personalized Electrode for Transcranial Electrical Stimulation

Santi G4, Cancelli A1,3, Cottone C1, Carducci F4and Tecchio F1,2*

1Department of Neuroscience, Laboratory of Electrophysiology for Translational neuroscience (LET’S) e ISTC e CNR, Fatebenefratelli Hospital, Rome, Italy

2Department of Neuroimaging, IRCCS San Raffaele Pisana, Rome, Italy

3Department of Geriatrics, Neurosciences and Orthopaedics, Institute of Neurology, Catholic University of Sacred Heart, Rome, Italy

4Department of Physiology and Pharmacology, Neuroimaging Laboratory, University of Rome “Sapienza”, Italy

*Corresponding Author:
Franca Tecchio
Laboratory of Electrophysiology for Translational
neuroscience (LET’S) e ISTC e CNR
Department of Neuroscience, Fatebenefratelli Hospital
Rome, Italy
Tel: +39 06 6837382
Fax: +39 06 6837382
E-mail: [email protected]

Received Date: December 18, 2015; Accepted Date: December 27, 2015; Published Date: January 30, 2016

Citation:Santi G, Cancelli A, Cottone C, Carducci F, Tecchio F (2016) Automatized Procedure to Shape a Regional Personalized Electrode for Transcranial Electrical Stimulation. J Bioengineer & Biomedical Sci S3:001. doi:10.4172/2155-9538.S3-001

Copyright: © 2016 Santi G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Objective: The purpose of this study is to obtain/create/develop an automatized procedure to personalize electrodes for transcranial electrical stimulation (tES) using individual brain magnetic resonance images (MRI). The electrode thus matches the individual cortical folding of the whole body bilateral primary somatosensory cortex (S1RePE). The selection of a specific regional brain target is a crucial part of any neuromodulation intervention, which is a promising tool in the enhancement of recovery from neurological or psychiatric damages.

Methods: By employing highly standardized MRI analysis software, we developed an automatized procedure for S1RePE shaping. We applied this procedure in 14 healthy people and assessed the accuracy of the procedure by comparing the automatized S1RePE with that which was manually traced in individual brain 3D MRI.

Results: In all subjects, the automatic and manual procedures were highly consistent, with mean Euclidean distance of 2.3 mm and mean intra-class correlation 0.995.

Conclusion: We successfully developed an automatized procedure, which is simpler, more replicable and requires less time than the procedure used up to this point in shaping S1RePE. Significance: We provide an automatic procedure using the individual cerebral MRI exam to shape a tES personalized electrode that matches the individual cortical folding. This automatic procedure can be adapted to any cortical region in the case that a specific cortical sulcus demarcates it.


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