alexa Autophagy and Cancer Chemotherapy: Inhibition or Enhancement?
ISSN: 2168-9431

Single Cell Biology
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Commentary

Autophagy and Cancer Chemotherapy: Inhibition or Enhancement?

Janice M Santiago-O’Farrill, Zhen Lu* and Robert C Bast Jr*

Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

*Corresponding Author:
Robert C Bast Jr
Department of Experimental Therapeutics
University of Texas MD Anderson Cancer Center
Houston, Texas, USA
Tel: +1 713-792-2121
E-mail: [email protected]
 
Zhen Lu
Department of Experimental Therapeutics
University of Texas MD Anderson Cancer Center
Houston, Texas, USA
Tel: +1 713-792-2121
E-mail: [email protected]

Received Date: June 03, 2016; Accepted Date: June 30, 2016; Published Date: July 02, 2016

Citation: Santiago-O’Farrill JM, Lu Z, Bast RC (2016) Autophagy and Cancer Chemotherapy: Inhibition or Enhancement?. Single Cell Biol 5:145. doi: 10.4172/2168-9431.1000145

Copyright: © 2016 Santiago-O’Farrill JM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Cells that encounter diverse stressful conditions such as hypoxia and starvation undergo an evolutionarily conserved process called autophagy. Autophagy is a cellular degradative mechanism whereby long-lived proteins and damaged organelles are sequestered within intracytoplasmic double walled autophagosomes that fuse with lysosomes where proteins and lipids are hydrolyzed into amino and fatty acids that can provide energy in nutrient poor conditions. The importance of this cellular process has been established in different physiological and pathological conditions such as aging, neurodegenerative diseases and cancer.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]nline.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords