alexa Axonal Neuropathy as a Rare Side Effect of Sulfasalazin
ISSN: 2165-7920

Journal of Clinical Case Reports
Open Access

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Case Report

Axonal Neuropathy as a Rare Side Effect of Sulfasalazine

Jamila Essouiri*, Amina Mounir, Fatima Ezzahra Abourazzak and Taoufik Harzy

Rheumatology Department, Medical School, Sidi Mohammed Ibn Abdellah University, Hassan II University Hospital, Fez, Morocco

*Corresponding Author:
Jamila Essouiri
Rheumatology Department, Medical School
Sidi Mohammed Ibn Abdellah University
Hassan II University Hospital, Fez, Morocco
Tel: +212 5356-09660
E-mail: [email protected]

Received date: June 17, 2016; Accepted date: September 22, 2016; Published date: September 27, 2016

Citation: Essouiri J, Mounir A, Abourazzak FE, Harzy T (2016) Axonal Neuropathy as a Rare Side Effect of Sulfasalazine. J Clin Case Rep 6:874. doi: 10.4172/2165-7920.1000874

Copyright: © 2016 Essouiri J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Sulphasalazine, one of the 5-aminosalicylates, is widely used for the treatment of inflammatory bowel diseases and arthritis. Beside its classic adverse effects like blood dyscrasias and hepatic failure, peripheral neuropathy has been reported as a rare adverse drug reaction to sulphasalazine. The mechanism of this neurotoxicity is unknown tell nowaday. We report a case of neurotoxicity that occurs after prolonged use of sulphasalazine. Previously, reported cases of neurotoxicity have not shown improvement of electric signs in nerve conduction study after stopping treatment.


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