alexa Bacterial Etiology of Necrotic Arachnidism in Black Wid
ISSN: 2161-0495

Journal of Clinical Toxicology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Bacterial Etiology of Necrotic Arachnidism in Black Widow Spider Bites

Bradley Ahrens1* and Carlos Crocker1,2

1Western University of Health Sciences, College of Veterinary Medicine, Pomona, CA

2St. Matthew’s University, College of Veterinary Medicine, Grand Cayman, Cayman Islands, BWI

*Corresponding Author:
Bradley Ahrens
Western University of Health Sciences
College of Veterinary Medicine, Pomona, CA
E-mail: [email protected]

Received Date: September 22, 2011; Accepted Date: November 03, 2011; Published Date: November 10, 2011

Citation: Ahrens B, Crocker C (2011) Bacterial Etiology of Necrotic Arachnidism in Black Widow Spider Bites. J Clinic Toxicol 1:106. doi: 10.4172/2161-0495.1000106

Copyright: © 2011 Ahrens B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Spider bites are a common challenge for physicians and veterinarians worldwide. Envenomation by the Western Black Widow (Latrodectus hesperus) is frequently associated with a necrotic cutaneous reaction at the bite site; a condition known as necrotic arachnidism. Although the composition of venom is known to be almost entirely neurotoxic, and thus, presumably not damaging to skin, varying degrees of dermal necrosis are commonly encountered at the site of envenomation. The underlying mechanism is unknown, prompting our investigation of the possibility for a bacterial etiology of the local lesions associated with the bite. This descriptive study reports the presence of 5 uncommon, highly pathogenic; multiple antibiotic resistant, bacterial species cultured from 220 pairs of sterilely extracted black widow spider fangs. This finding is consistent with the known unresponsiveness of cutaneous spider bite lesions to steroids and first-line antibiotic treatment; which has led to the misconception that the venom is the causative agent. This discovery supports our hypothesis that bacterial strains have adapted to life on the fangs of certain spiders; providing them with an excellent mode of infection by not only being passed subcutaneously to the victim, but also protected from host defenses by the immunosuppressive effects of the venom. Since current treatment protocols for spider envenomations concentrate almost solely on the local and systemic effects of the venom itself, our findings suggest that the current diagnostic algorithm and treatment standards for spider bites in both human and animal medicine may be inadequate and should be re-assessed.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords