alexa Base Catalyzed Glycerolysis of Ethyl Acetate
ISSN: 2161-0401

Organic Chemistry: Current Research
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Research Article

Base Catalyzed Glycerolysis of Ethyl Acetate

Pranita P. Kore*, Snehal D. Kachare, Sandip S. Kshirsagar and Rajesh J. Oswal
Department of Pharmaceutical Chemistry, JSPM’s Charak College of Pharmacy and Research, Gat No. 720/1&2, Wagholi, Pune-Nagar Road, Pune-412207, Maharashtra, India
Corresponding Author : Pranita P. Kore
Department of Pharmaceutical Chemistry
JSPM’s Charak College of Pharmacy and Research
Gat No. 720/1&2, Wagholi
Pune-Nagar Road, Pune-412207
Maharashtra, India
Tel: +9120-27051172
Fax: +9120-27052590
E-mail: [email protected]
Received August 24, 2012; Accepted September 17, 2012; Published September 20, 2012
Citation: Kore PP, Kachare SD, Kshirsagar SS, Oswal RJ (2012) Base Catalyzed Glycerolysis of Ethyl Acetate. Organic Chem Curr Res 1:108. doi:10.4172/2161-0401.1000108
Copyright: © 2012 Kore PP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Glycerol is a simple polyol compound widely used as a green solvent, having backbone to all lipids known as
triglycerides. In our present study, we used glycerol as an acyl acceptor for transesterification of aliphatic acetate by
conventional and using microwave assisted synthesis. It was found that increase in the concentration of substrate and
catalysts with reaction time, increases yield of aliphatic alcohols. The reaction was followed by separation of product
from glycerol by simple extraction with diethyl ether and studied for their HPLC and GC analysis.


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