alexa Benefit of Glycemic Control for Reducing the Effects of
ISSN: 2155-6156

Journal of Diabetes & Metabolism
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Benefit of Glycemic Control for Reducing the Effects of Air Pollution on Blood Pressure: A Panel Study

Youn-Hee Lim1, Ho Kim2, Jin Hee Kim3, Sanghyuk Bae4, Hye Yin Park5, Hyun Joo Bae6, Hee Lak Choi7 and Yun-Chul Hong3,8*

1Institute of Health and Environment, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea

2Department of Epidemiology and Biostatistics, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea

3Institute of Environmental Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea

4Environmental Health Center, Seoul National University College of Medicine, Seoul, Republic of Korea

5Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea

6Korea Environment Institute, Seoul, Republic of Korea

7National Institute of Environmental Research, Incheon, Republic of Korea

8Institute of Medical Research, Seoul National University Bundang Hospital, Seongnam, Republic of Korea

*Corresponding Author:
Yun-Chul Hong
Institute of Environmental Medicine
Seoul National University Medical Research Center
103 Daehakro, Jongro-gu, Seoul 110-799, Republic of Korea
Tel: +82-2-740-8394
Fax: +82-2-747-4830
E-mail: [email protected]

Received date: June 27, 2014; Accepted date: September 16, 2014; Published date: September 24, 2014

Citation: Lim YH, Kim H, Kim JH, Bae S, Park HY, et al. (2014) Benefit of Glycemic Control for Reducing the Effects of Air Pollution on Blood Pressure: A Panel Study. J Diabetes Metab 5:434 doi: 10.4172/2155-6156.1000434

Copyright: © 2014 Lim YH, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Objective: Diabetes mellitus (DM) is known to aggravate the association between air pollution and cardiovascular diseases, such as hypertension. However, the influence may differ based on the degree of glycemic control. Therefore, we hypothesized that the adverse effects of air pollutants on Blood Pressure (BP) in patients with controlled DM would be less than those in patients with uncontrolled DM.

Methods: Data were analyzed from a panel study of 560 elderly participants, conducted between 2008 and 2010 in Seoul, Korea. Mixed effects models were used to assess the association of air pollutants [particulate matter with aerodynamic diameters<10 μm (PM10), PM2.5, PM10-2.5, nitrogen dioxide, ozone, sulfur dioxide, and carbon monoxide] with BP. We compared the magnitude of the effects among individuals with controlled and uncontrolled DM and those without DM.

Results: Increases in the interquartile range levels of PM10 were significantly associated with 2.0 mmHg (95% CI, 0.7–41.7 mmHg) increases in systolic BP (SBP) and 2.0 mmHg (95% CI, 1.2–41.7 mmHg) increases in diastolic BP (DBP) when we analyzed all participants. Most of the other air pollutants, except ozone, were also associated with significant increases in BP. When we compared the BP changes among the three groups (non-DM, controlled DM, and uncontrolled DM), significant increases in SBP and DBP were observed in participants with uncontrolled DM and those without DM; significant BP increases were not observed in participants with controlled DM.

Conclusion: Glycemic control provided benefits for alleviating BP changes associated with exposure to air pollutants.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords