Bet v 2 Responsibility in Birch-Induced SymptomsMetz Favre C1*, Pauli G1, Castro L2, Valenta R3 and de Blay F1
- *Corresponding Author:
- Favre Metz Carine
Division of Asthma and Immuno-Allergology
Department of Chest Diseases University Hospital
E-mail: [email protected]
Received date: February 20, 2014; Accepted date: March 25, 2014; Published date: March 30, 2014
Citation: Metz Favre C, Pauli G, Castro L, Valenta R, de Blay F (2014) Bet v 2 Responsibility in Birch-Induced Symptoms. J Allergy Ther 5:169. doi: 10.4172/2155-6121.1000169
Copyright: © 2014 Metz Favre C, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
We report the case of a patient who first had grass pollinosis associated to food allergy, especially melon, and who developed secondarily early spring pollinosis which could be related to sensitization to the birch profilin. This patient, whose birch pollinosis was confirmed by nasal provocation test, was not sensitized to Bet v 1, the major birch pollen allergen in North Western Europe. We demonstrated by inhibition studies using grass and birch profilins that the clinical birch allergy was induced by the cross reacting profilin present both in birch and grass pollen and also in melon.