alexa Beware of Paracetamol Toxicity
ISSN: 2161-0495

Journal of Clinical Toxicology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article

Beware of Paracetamol Toxicity

Vidhya Malar HL* and S Mary Mettilda Bai

P.G and Research Department of Zoology, Holy Cross College, Nagercoil- 629 004, Tamil Nadu, India

*Corresponding Author:
Vidhya Malar HL
P.G and Research Department of Zoology
Holy Cross College
Nagercoil- 629 004, Tamil Nadu, India
E-mail: [email protected]

Received date: August 14, 2012; Accepted date: September 13, 2012; Published date: September 15, 2012

Citation: Vidhya Malar HL, Mary Mettilda Bai S (2012) Beware of Paracetamol Toxicity. J Clinic Toxicol 2:142. doi: 10.4172/2161-0495.1000142

Copyright: © 2012 Vidhya Malar HL, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



The Effect of Paracetamol mechanism by which it works, metabolism, recommended doses, toxic dosage are discussed with study reports in this paper. Paracetamol shows some life threatening effects like Liver damage which in turn leads to live failure and death. Though it reduces fever and pain, it is found highly toxic. The mechanism by which Paracetamol reduces fever and pain is still not known. On metabolism, Paracetamol is converted to a metabolite which is very toxic to liver cells. In recommended doses (1-2 g/day), Paracetamol does not irritate stomach lining, kidney cells and liver cells. Studies reported that high dosage (>2 g/day), resulted in Gastrointestinal complications, abnormal Kidney function, Liver damage.

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version