alexa Bifidobacterium breve M4A and Bifidobacterium longum su
ISSN: 2329-8901

Journal of Probiotics & Health
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Bifidobacterium breve M4A and Bifidobacterium longum subsps. longum FA1 Reduced Weight Gain and Hepatic Lipid Droplets in Young Mice Fed High-Fat

Mustafa Alsharafani1*, Martin Roderfeld2, Elke Roeb2 and Michael Krawinkel1

1Institute of Nutritional Sciences, Justus Liebig University, Wilhelm Str, Giessen, Germany

2Department of Gastroenterology, Uniklinikum Giessen and Marburg GmbH, Centre for Internal Medicine, Justus Liebig University, Klinik Str, Giessen, Germany

*Corresponding Author:
Mustafa Alsharafani
institute of Nutritional Sciences, Justus Liebig
University, Wilhelm Str, 20/35392 Giessen, Germany
Tel: +490641/9939035
Fax: +490641/9939039
E-mail: [email protected]

Received date: May 23, 2016; Accepted date: August 03, 2016; Published date: August 13, 2016

Citation: Alsharafani M, Roderfeld M, Roeb E, Krawinkel M (2016) Bifidobacterium breve M4A and Bifidobacterium longum subsps. longum FA1 Reduced Weight Gain and Hepatic Lipid Droplets in Young Mice Fed High-Fat. J Prob Health 4:151. doi: 10.4172/2329-8901.1000151

Copyright: © 2016 Alsharafani M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Among commensal bacteria, Bifidobacteria (B) is one of the most numerous probiotics in the mammalian gut. The goal of the study was to evaluate the in vivo anti-obesity effect of B. breve M4A and B. longum subsp. longum FA1 in young mice fed a high-fat diet (HFD). Three (male mice C57BL/6JRj) groups, the model HFD group and treatment (HFD-FA1 and HFD-M4A) groups were fed an HFD to induce obesity. After feeding the mice a HFD for six weeks, animals receiving B. breve M4A and B. longum subsp. longum FA1 had significantly lower (p<0.01) weight gain compared to mice fed a high-fat diet only. Mice fed B. breve M4A supplemented with 0.3% yeast extract and 3% glucose exhibited significantly lower serum triglycerides (p<0.05) compared with the HFD group. The daily consumption (2.9 × 106 CFU/day) of B. longum subps. longum FA1 and (4.1 × 106 CFU/day) B. breve M4A (p<0.01) significantly increased the amount of bifidobacteria and lactic acid bacteria in the cecal content. This study showed that Bifidobacterium species reduced weight gain and hepatitis lipid droplets. Thus, bifidobacteria supplementation may be one mean for reducing obesity and related chronic Non-communicable diseases.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords