alexa Bioactive Lignans: A Survey Report on their Chemical Structures?
ISSN: 2329-6836

Natural Products Chemistry & Research
Open Access

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Bioactive Lignans: A Survey Report on their Chemical Structures?

Ahmed E Fazary1,2*, Mohammad Y Alfaifi3, Kamel A Saleh3, Mohammed A Alshehri3 and Serag Eldin I Elbehairi2

1Chemistry Department, Faculty of Science, King Khalid University, Abha 9004, Saudi Arabia

2Applied Research Sector, Egyptian Organization for Biological Products and Vaccines (VACSERA Holding Company), 51 Wezaret El Zeraa Street, Agouza, Giza, Egypt

3Biology Department, Faculty of Science, King Khalid University, Abha 9004, Saudi Arabia

Corresponding Author:
Ahmed E Fazary
Chemistry Department, Faculty of Science
King Khalid University, Abha 9004, Saudi Arabia
Tel: +96672418343
E-mail: [email protected] (or) [email protected]

Received date: April 14, 2016; Accepted date: May 25, 2016; Published date: May 25, 2016

Citation: Fazary AE, Alfaifi MY, Saleh KA, Alshehri MA, Elbehairi SEI (2016) Bioactive Lignans: A Survey Report on their Chemical Structures? Nat Prod Chem Res 4:226. doi:10.4172/2329-6836.1000226

Copyright: © 2016 Fazary AE, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Lignans are polyphenols spread in a wide variety of plant-based foods, including seeds, whole grains, legumes, fruit, and vegetables. When consumed, lignan precursors are converted to the enterolignans, enterodiol and enterolactone, by bacteria that normally colonize the human intestine. Lignans have attracted considerable attention due to their pharmacological and biological activities. This review article is a survey on the molecular structure of about 276 new naturally occurring lignans obtained from different plant families. We classified seven main types according to their structural features, and provided a number of review reports published recently about lignans. A tabular compilation of the molecular structures of known lignans is presented at the end of this survey report. A total of 111 references were considered for this survey report.


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