alexa Bioavailability Study of Sustain Release Preparations of Three Widely used NSAIDS Available in Bangladesh | OMICS International | Abstract
ISSN : 2153-2435

Pharmaceutica Analytica Acta
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Bioavailability Study of Sustain Release Preparations of Three Widely used NSAIDS Available in Bangladesh

Md. Sohel D1,2*, Nusrat T1, Sultana T1,2, Md. Kawsar H1, Md. Helal1, Sumon U3, Md. Islam T4

1Department of Pharmacy, State University of Bangladesh, Dhanmondi, Dhaka, Bangladesh

2Incepta Pharmaceuticals Ltd, Dewan Idris Road, Zirabo, Savar, Dhaka, Bangladesh

3Department of Pharmacy, University of Asia Pacific, Dhanmondi, Dhaka, Bangladesh

4Department of Pharmacy, Southeast University, Banani, Dhaka, Bangladesh

*Corresponding Author:
Md. Sohel D
Department of Pharmacy, State University of Bangladesh
Dhanmondi, Dhaka-1205, Bangladesh
Tel: +8801916016974
E-mail: [email protected]

Received date: Apr 24, 2016; Accepted date: May 20, 2016; Published date: May 23, 2016

Citation: Md. Sohel D, Nusrat T, Sultana T, Md. Kawsar H, Md. Helal, Sumon U, Md. Islam T (2016) Bioavailability Study of Sustain Release Preparations of Three Widely used NSAIDS Available in Bangladesh. Pharm Anal Acta 7:482. doi:10.4172/2153-2435.1000482

Copyright: © 2016 Md. Sohel et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

This research has been designed to assess the in vitro bioavailability study of widely distributed and commonly used three analgesic and anti-pyretic drugs namely Diclofenac Sodium, Paracetamol and Ibuprofen sustained release tablets. Three brands of Diclofenac Sodium, four brands of Paracetamol and three brands of Ibuprofen tablets were obtained. Three brands of Diclofenac SR tablets, all brands maintained a steady state release pattern throughout the defined period, i.e. 12 hours. In 1st hour sample D01, D02, D03 were released 43.6%, 36.16%, and 59.85% of drug in dissolution respectively. Four brands of Paracetamol SR tablets, all brands maintained a steady state release pattern throughout the defined period, i.e. 12 hours. In 1st hour sample P01, P02, P03 and P04 were released 78.60%, 89.36%, 74.21%, 78.14 of drug in phosphate buffer (pH 6.8) respectively. Another sustained release tablets was Ibuprofen; all brands maintained a steady state release pattern trough out the defined period, i.e. 12 hours. In 1st hour sample I01, I02, I03 were released 60.46%, 54.02%, 50.57% of drug in phosphate buffer (pH 6.8) respectively. The release rates of the samples were determined for around 12th hours.

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version