Biofilm Related to Animal Health, Zoonosis and Food Transmitted Diseases: Alternative Targets for Antimicrobial Strategy?
- *Corresponding Author:
- Domenico Schillaci
Department of STEMBIO
Università degli Studi di Palermo
Via Archirafi 32
E-mail: [email protected]
Received Date: September 21, 2012; Accepted Date: September 22, 2012; Published Date: September 25, 2012
Citation: Schillaci D, Vitale M (2012) Biofilm Related to Animal Health, Zoonosis and Food Transmitted Diseases: Alternative Targets for Antimicrobial Strategy? J Microbial Biochem Technol 4: vii-x. doi: 10.4172/1948-5948.1000e108
Copyright: © 2012 Schillaci D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The biofilm is a complex community of microbial cells that are associated with a surface and enclosed in a self-produced biopolymer matrix. Such structured community is a response of bacteria to a signal system named quorum sensing (QS) constituted by inter-cell communication through the production of small molecules called autoinducers (AIs) that trigger a cascade of events in gene expression. When the concentration of the AIs molecules reach a certain threshold, the bacterial population acts as a single organism, collectively expressing virulence or biofilm forming genes. Gram-positive bacteria use modified oligopeptides as QS effectors molecules.