Bioinformatic Approach for the Identification of Hepatitis B Viral Insert in The Exon Region of Human Genome
P. Pandarinath*, M. Shashi and A. Appa Rao
Department of Computer Sciences, College of Engineering (A) Andhra University, Visakhapatnam, India
- *Corresponding Author:
- Dr. P. Pandarinath
Department of Computer Sciences
College of Engineering (A) Andhra University
Visakhapatnam, Andhra Pradesh, India
E-mail: [email protected]
Received Date:November 12, 2010; Accepted Date: November 18, 2010; Published November 21, 2010
Citation: Pandarinath P, Shashi M, Appa Rao A (2010) Bioinformatic Approach for the Identification of Hepatitis B Viral Insert in The Exon Region of Human Genome. J Comput Sci Syst Biol 3:089-090. doi: 10.4172/jcsb.1000064
Copyright: © 2010 Pandarinath P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Hepatitis B viral sequence was downloaded from NCBI Tax Browser and scanned against complete genome of Homo sapiens for the presence of possible viral inserts in human genome. The alignments which showed more than 25-30 residues, 90-100 % identities and localization in the exon regions were only considered. The results from the computational analysis revealed that Hepatitis B virus resulted in viral segment inserted in the exon region of human genome.