alexa Biomarkers in Acute Myocardial Infarction | OMICS International | Abstract
ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
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Review Article

Biomarkers in Acute Myocardial Infarction

M. Imteyaz Ahmad1* and Neera Sharma2
1Department of Biochemistry, PGIMER & Dr. Ram Manohar Lohia Hospital, New Delhi, India
2Department of Laboratory Medicine, PGIMER & Dr. Ram Manohar Lohia Hospital, New Delhi, India
Corresponding Author : Dr. Imteyaz Ahmad
Department of Biochemistry
NursinghHome lab, Room no.20.
Dr Ram Manohar Lohia Hospital
Baba kharak singh marg, New Delhi
PIN 110001, India
Tel: +919953130525
E-mail: [email protected]
Received: October 22, 2012; Accepted: November 09, 2012; Published: November 12, 2012
Citation: Ahmad MI, Sharma N (2012) Biomarkers in Acute Myocardial Infarction. J Clin Exp Cardiolog 3:222. doi:10.4172/2155-9880.1000222
Copyright: © 2012 Ahmad MI, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Acute coronary syndrome (ACS) is a significant cause of morbidity and mortality worldwide. Patients can be stratified by symptoms, risk factors and electrocardiogram results but cardiac biomarkers also have a prime role both diagnostically and prognostically. The proper diagnosis of ACS requires reliable and accurate biomarker assays to detect evidence of myocardial necrosis. Currently, troponin is the gold standard biomarker for myocardial injury and is used commonly in conjunction with creatine kinase-MB (CK-MB) and myoglobin to enable a more rapid diagnosis of ACS. Other markers of myocardial necrosis, inflammation and neurohormonal activity have also been shown to have either diagnostic or prognostic utility, but none have been shown to be superior to troponin. The measurement of multiple biomarkers and the use of point of care markers may accelerate current diagnostic protocols for the assessment of such patients

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