alexa Biophysical EPR Studies Applied to Membrane Proteins | OMICS International | Abstract
ISSN: 2161-0398

Journal of Physical Chemistry & Biophysics
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Review Article

Biophysical EPR Studies Applied to Membrane Proteins

Indra D Sahu and Gary A Lorigan*
Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, United States of America
Corresponding Author : Gary A. Lorigan
Department of Chemistry and Biochemistry
Miami University, Oxford, OH 45056, USA
Tel: (513) 529-2813
Fax: (513) 529-5715
E-mail: [email protected]
Received September 16, 2015; Accepted November 05, 2015; Published November 10, 2015
Citation: Sahu ID, Lorigan GA (2015) Biophysical EPR Studies Applied to Membrane Proteins. J Phys Chem Biophys 5:188. doi:10.4172/2161-0398.1000188
Copyright: © 2015 Sahu ID, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Membrane proteins are very important in controlling bioenergetics, functional activity, and initializing signal pathways in a wide variety of complicated biological systems. They also represent approximately 50% of the potential drug targets. EPR spectroscopy is a very popular and powerful biophysical tool that is used to study the structural and dynamic properties of membrane proteins. In this article, a basic overview of the most commonly used EPR techniques and examples of recent applications to answer pertinent structural and dynamic related questions on membrane protein systems will be presented.

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