Reach Us +1-947-333-4405
Bleeding Kinetics after Total Hip or Knee Replacement: A Prospective Observational Study | OMICS International | Abstract
ISSN: 2155-6148

Journal of Anesthesia & Clinical Research
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Bleeding Kinetics after Total Hip or Knee Replacement: A Prospective Observational Study

Thomas Giral1*, Antoine Tesniere1 , Lorenn Bellamy1 , Yves Ozier2 , Charles Marc Samama1 and Nadia Rosencher1

1Department of Anesthesia and Intensive Care, Cochin University Hospital, Assistance Publique, Hopitaux de Paris, University Paris Descartes, Paris, France

2Division of Anesthesia, Intensive Care and Emergency Medicine, Brest University Hospital, Brest, France

*Corresponding Author:
Thomas Giral
Department of Anesthesia and Intensive Care
Cochin University Hospital, Assistance Publique
Hopitaux de Paris, University Paris Descartes, Paris, France
Tel: +33 6 86 32 66 23
E-mail: [email protected]

Received Date: September 14, 2013; Accepted Date: September 28, 2013; Published Date: September 30, 2013

Citation: Giral T, Tesniere A, Bellamy L, Ozier Y, Samama CM, et al. (2013) Bleeding Kinetics after Total Hip or Knee Replacement: A Prospective Observational Study. J Anesth Clin Res 4:355.doi: 10.4172/2155-6148.1000355

Copyright: © 2013 Giral T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Background and objectives: The objective was to assess the kinetics of postoperative bleeding after total hip or knee replacement, with or without administration of tranexamic acid, in order to anticipate red blood cell transfusion thresholds in the recovery room.

Materials and methods: This was a prospective, observational, single-center study. All patients undergoing primary or revision total hip or knee replacement were enrolled for two months. Patients were managed using a multimodal strategy designed to reduce the need for red blood cell transfusion. Postoperative bleeding kinetics was assessed according to the drop of hemoglobin levels between the arrival in the recovery room and day one after surgery.

Results: A total of 106 patients were included. The mean transfusion rate was 18%. Nadir hemoglobin levels were observed on day + 2, and about 60% of bleeding occurred during the postoperative period, with a drop of 1.2 ± 0.2 g/dL between the recovery room and day one for patients receiving tranexamic acid, and 1.9 ± 0.2 g/dL for those not receiving tranexamic acid (p=0.018).

Discussion: In our center, the hemoglobin transfusion threshold in recovery room might be raised by 1 or 2 g/ dL depending on whether tranexamic acid is used.


Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri and Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]m

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry


[email protected]

1-702-714-7001Extn: 9042

© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version