Body Surface Changes in Gastrointestinal Helminthes Following in vitro Treatment with Allium sativum Oil
Hatem A Shalaby* and Tarek K Farag
Department of Parasitology and Animal Diseases, National Research Center, Giza, Egypt
- *Corresponding Author:
- Hatem A Shalaby
Department of Parasitology and Animal Diseases
National Research Center, Egypt
Tel: 020 3371615
Fax: 020 3370931
E-mail: [email protected]
Received date: December 06, 2013; Accepted date: January 09, 2014; Published date: January 13, 2014
Citation: Shalaby HA, Farag TK (2014) Body Surface Changes in Gastrointestinal Helminthes Following in vitro Treatment with Allium sativum Oil. J Veterinar Sci Technol 5:153. doi:10.4172/2157-7579.1000153
Copyright: © 2014 Shalaby HA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
A scanning electron microscopic study was undertaken to assess, for the first time, whether Allium sativum oil (ASO) extract had any effect on helminthes’ body surface following 24 h incubation in vitro. Two species of gastrointestinal helminthes, of most economic significance in sheep, Haemonchus contortus and Moniezia expansa were collected from naturally infected sheep slaughtered in Cairo abattoir, then exposed to 10, 50, 100 μg/ml ASO. The body surface of these helminthes was observed to be affected and altered by ASO. These changes were concentration dependent, and consisted of destructive alterations and deformity in the cuticle of H. contortus and also in the tegumental architecture of M. expansa. The current study confirmed that an alternative, effective and natural anthelmintic could be developed using garlic.