alexa Bolnav cu Gist Gastric Gigant; Supravieand#539;uire Nesperatand#259; Prezentare de Caz | OMICS International | Abstract
[Jurnalul de Chirurgie]
ISSN: 1584-9341

Journal of Surgery
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Case Report

Bolnav cu Gist Gastric Gigant; Supraviețuire Nesperată Prezentare de Caz

Gheorghe M1*, Predescu D1, Copca N2, Cristina Iosif3, Băcanu F4 and Constantinoiu S1

1Clinica de Chirurgie Generală și Esofagiană, Spitalul Clinic Sfânta Maria București, Universitatea de Medicină și Farmacie Carol Davila” București, Romania

2Centrul de Cercetare Chirurgie, Spitalul Clinic Sfânta Maria București, Universitatea de Medicină și Farmacie Carol Davila” București, Romania

3Departamentul de Anatomie Patologică, Spitalul Clinic Sfânta Maria București, Universitatea de Medicină și Farmacie Carol Davila” București, Romania

4Departamentul de Oncologie, Spitalul Clinic Sfânta Maria București, Universitatea de Medicină și Farmacie Carol Davila” București, Romania

*Corresponding Author:
Mircea Gheorghe, MD
Department of General and Esophagian Surgery
"St. Mary" Hospital București, Bd. Ion Mihalache
No 37-39, Sector 1, București, Romania
Tel: +40 (0) 721 22 60 20
Fax: 0040721226020
E-mail: [email protected]

Received date: November 10, 2013; Accepted date: February 27, 2014; Published date: May 09, 2014

Citation: Gheorghe M, Predescu D, Copca N, Iosif C and Bacanu F (2014) Bolnav cu Gist Gastric Gigant; Supraviețuire Nesperată Prezentare de Caz. Journal of Surgery [Jurnalul de Chirurgie] 10:17:74-77. doi: 10.7438/1584-9341-10-1-17

Copyright: © 2014 Gheorghe M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

Abstract

Background: Gastrointestinal Stromal Tumors (GIST) are rare neoplasms, with sever prognosis in advanced cases. Until the discovery of Tyrosin Kinase Inhibitors (TKI), the life expectancy was very poor for patient with metastatic tumors, postoperative relapses or unresectable disease. Introduction of TKI therapy provided an unexpected survival rate, controlling the disease with very good tolerance. Method: We present a case report representative for GIST pathology. It is the first case of our GIST series of patients, operated in General and Esophageal Surgery Clinic of “St. Mary” Hospital Bucharest. A multidisciplinary approach and a complex, multimodal, surgical and oncological treatment was applied, with good response confirmed by the long-term follow-up. A 79 years old patient was diagnosed in 2004 (at the age of 70 years) with giant gastric GIST. He underwent a total gastrectomy, splenectomy and left pancreatectomy; the resection was considered as R1 because the tumor capsule was not complete. The adjuvant treatment with TKI was started postoperatively for 2 years. The recurrence was noted one year after the adjuvant therapy stop. Then the TKI treatment was restarted with very good tolerance and control of disease at 9 years. Conclusion: The TKI therapy allows long-term control of the malignant GISTs in term of overall survival and quality of life, even when the surgical procedure is not optimal.

Keywords

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7