alexa Bone Health in Children with Duchenne Muscular Dystrophy: A Review
ISSN: 2161-0665

Pediatrics & Therapeutics
Open Access

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Review Article

Bone Health in Children with Duchenne Muscular Dystrophy: A Review

Nadia Perera1 and Michelle Farrar1,2*

1Discipline of Pediatrics, The University of New South Wales, Australia

2Department of Neurology, Sydney Children’s Hospital, Australia

*Corresponding Author:
Michelle Farrar
Department of Neurology
Sydney Children’s Hospital
High St, Randwick. NSW. 2031, Australia
Tel: +61 2 93821549
Fax: +61 2 93821580
E-mail: [email protected]

Received Date: July 24, 2015; Accepted Date: August 17, 2015; Published Date: August 19, 2015

Citation: Perera N, Farrar M (2015) Bone Health in Children with Duchenne Muscular Dystrophy: A Review. Pediat Therapeut 5:252. doi: 10.4172/2161-0665.1000252

Copyright: © 2015 Perera N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Duchenne muscular dystrophy (DMD) patients are vulnerable to osteoporosis and fractures. This has significant impact on the mobility and quality of life of DMD patients, making the development of strategies to prevent of treat these complications critical. As such, this review incorporates a discussion of the determinants of bone health in healthy children, followed by an examination of bone health in DMD, with a particular focus of vitamin D deficiency and its implications. An illustrative case study highlights the bone-related complications that can occur in DMD and assessment approach.

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