Bone Marrow Histology in CML: A Continuing RelevancePrashant Sharma1*Tejinder Singh2
- Corresponding Author:
- Prashant Sharma
Assistant Professor, Haematology Department
Level 5, Research Block A, Sector 12
Postgraduate Institute of Medical Education and Research
Chandigarh 160012, India
Tel: +91 88 72016123
E-mail: [email protected]
Received Date: January 24, 2013; Accepted Date: March 25, 2013; Published Date: March 27, 2013
Citation: Prashant S, Tejinder S (2013) Bone Marrow Histology in CML: A Continuing Relevance. J Bone Marrow Res 1:107. doi:10.4172/2329-8820.1000107
Copyright: © 2013 Prashant S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
A Bone Marrow Biopsy (BMB), though not essential for diagnosing Chronic Myeloid Leukemia (CML) in chronic phase, remains a firstline investigation in the work-up, prognostication and follow-up of this disorder. It demonstrates histological and topographic features, proliferation patterns, detects CML metamorphosis and fibrosis and is indispensable in the investigation of unexplained cytopenias during therapy.