alexa Bone Metastasis from Parathyroid Carcinoma Non-avid for 99mTc-MIBI, 99mTc-MDP, and 18F-FDG | OMICS International
ISSN: 2155-9619

Journal of Nuclear Medicine & Radiation Therapy
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Case Report

Bone Metastasis from Parathyroid Carcinoma Non-avid for 99mTc-MIBI, 99mTc-MDP, and 18F-FDG

Maomei Ruan1, Yan Shen2,3, Huizhen Zhang4, Minghua Li3 and Libo Chen1*

1Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, China

2Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, China

3Institute of Interventional and Diagnostic Radiology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, China

4Department of Pathology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, China

Corresponding Author:
Libo Chen, MD
Department of Nuclear Medicine
Shanghai Jiao Tong University Affiliated Sixth People’s Hospital
600 Yishan Road, Shanghai 200233, People’s Republic of China
Tel: +86-21-64369181
Fax: +86-21-64701361
E-mail: [email protected]

Received Date: December 18, 2013; Accepted Date: January 23, 2014; Published Date: January 31, 2014

Citation: Ruan M, Shen Y, Zhang H, Li M, Chen L (2014) Bone Metastasis from Parathyroid Carcinoma Non-avid for 99mTc-MIBI, 99mTc-MDP, and 18F-FDG. J Nucl Med Radiat Ther 5:165. doi:10.4172/2155-9619.1000165

Copyright: © 2014 Ruan M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Nuclear medicine imaging modalities have been reported to be useful in the diagnosis of parathyroid carcinoma (PC). However, false negative findings of bone metastasis from PC have been rarely reported. Here, we describe a patient undergoing nuclear medicine examinations since he had persistent high calcium and parathyroid hormone levels after resection of parathyroid tumor. 99mTc-Sestamibi (99mTc-MIBI) whole body scintigraphy (WBS) and 99mTc-methylene diphosphonate (99mTc-MDP) WBS were both negative. 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18FDG-PET/CT) scan demonstrated osteolytic lesion in the fourth lumbar vertebrae (L4) on CT image with no obvious 18F-FDG accumulation on PET image. CT-guided fine needle aspiration and pathalogical examinations confirmed bone metastasis from PC.

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