alexa Botulinum Toxin as a Stand-Alone Treatment for Muscle Spasticity: Review of the Evidence
ISSN: 2329-6895

Journal of Neurological Disorders
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Review Article

Botulinum Toxin as a Stand-Alone Treatment for Muscle Spasticity: Review of the Evidence

Abdel Magid O Bakheit*
Emeritus Professor of Neurological Rehabilitation, Moseley Hall hospital, United Kingdom
Corresponding Author : Abdel Magid O Bakheit, MD, PhD, FRCP
Emeritus Professor of Neurological Rehabilitation
Moseley Hall hospital, Alcester Road
Birmingham B13 8JL, United Kingdom
Tel: +44121-4666595
Fax: +44121- 4423694
E-mail: [email protected]
Received February 15, 2013; Accepted April 08, 2013; Published April 11, 2013
Citation: Bakheit AMO (2013) Botulinum Toxin as a Stand-Alone Treatment for Muscle Spasticity: Review of the Evidence. J Neurol Disord 1:109. doi: 10.4172/2329-6895.1000109
Copyright: © 2013 Bakheit AMO. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Botulinum toxin has been shown to reduce muscle tone and improve motor function in children and adults with muscle spasticity. However, it is not clear whether the magnitude and/ or the duration of the beneficial effect of this treatment are increased by combining it with other spasticity treatments. Nonetheless, some guidelines on the management of spasticity recommend that botulinum toxin is not used unless it is combined with other spasticity treatment modalities, such as physiotherapy. In this article it is argued that the clinical evidence that supports such recommendations is at best weak and that the recommendations are probably too restrictive. It is further suggested that the use of botulinum toxin as a stand-alone treatment of spasticity is justifiable, especially when other therapies are not immediately available for use in combination with the toxin.

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