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ISSN: 2161-0495

Journal of Clinical Toxicology
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Research Article

Botulism Beyond Radiologic Ileus

Mirna Krajina-Andricevic1*, Lada Zibar2, Tomislav Kremer1 and Jadranka Korda3

1Department of Internal Medicine, General Hospital Vinkovci, Vinkovci, Croatia

2Clinic of Internal Medicine, University Hospital Center, J. J. Strossmayer University, Osijek, Croatia

3Department of Infective Disease, General Hospital Vinkovci, Vinkovci, Croatia

*Corresponding Author:
Mirna Krajina-Andricevic
Department of Internal Medicine
General Hospital Vinkovci, Vinkovci, Croatia
E-mail: [email protected]

Received date: May 16, 2012; Accepted date: June 21, 2012; Published date: June 23, 2012

Citation: Krajina-Andricevic M, Zibar L, Kremer T, Korda J (2012) Botulism Beyond Radiologic Ileus. J Clinic Toxicol 2:128. doi: 10.4172/2161-0495.1000128

Copyright: © 2012 Krajina-Andricevic M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Botulism is a rare disease caused by Clostridium botulinum neurotoxin that irreversibly blocks releasing of acetylcholine on presynaptic cholinergic terminal of the autonomic nerves of the neuromuscular junction. Intoxication is most commonly reported in association with consumption of homemade canned or smoked products. Botulism is usually described as a potentially lethal disease, however, because the clinical presentation is dose-dependent, in some cases this disease can have a mild course and poorly defined symptoms. We present clinical findings of a 26 year old male patient who developed constipation, urine retention, blurred vision and weakness, after eating a homemade smoked ham. Our patient had mild form of botulism with no signs of respiratory distress and his treatment included only symptomatic measures. Laboratory diagnosis of botulism was obtained by the mouse bioassay (MBA) test which confirmed the presence of botulinum neurotoxin in the patient’s serum. The diagnosis of botulism is frequently missed or delayed in patients with mild clinical presentations because of the sporadic nature of cases and general unfamiliarity with the syndrome.

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