alexa Buprenorphine–Induced Urinary Hesitancy is Common and Managed with Ease: A Retrospective Chart Review
ISSN: 2329-6488

Journal of Alcoholism & Drug Dependence
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Review Article

Buprenorphine–Induced Urinary Hesitancy is Common and Managed with Ease: A Retrospective Chart Review

Anjali Varma1*, Jessica B Long2, Joseph Iskandar3 and Mamta Sapra4

1Mental Health Clinic and Lead Psychiatrist Buprenorphine Clinic, Veterans Affairs Medical Centre, Salem, VA 24153, USA

2Research and Development, Salem, VA 24153, USA

3Psychiatric Practice, Roanoke, Salem, USA

4Department of Psychiatry and Behavioral Medicine, Virginia Tech Carilion School of Medicine, Memory Assessment Clinic, Salem, VA 24153, USA

*Corresponding Author:
Anjali Varma
Director, Mental Health Clinic and Lead Psychiatrist Buprenorphine Clinic
Veterans Affairs Medical Centre
1970 Roanoke Blvd, Salem, VA, USA
Tel: 5409822463/3555
Fax: 540-855-3452
E-mail: [email protected]

Received Date: March 02, 2017; Accepted Date: April 06, 2017; Published Date: April 10, 2017

Citation: Varma A, Long JB, Iskandar J, Sapra M (2017) Buprenorphine–Induced Urinary Hesitancy is Common and Managed with Ease: A Retrospective Chart Review. J Alcohol Drug Depend 5:258. doi: 10.4172/2329-6488.1000258

Copyright: © 2017 Varma A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Buprenorphine is a partial agonist at the mu opioid receptor. As compared to methadone, it has the advantage of being used in office based treatment setting, making this a preferred treatment option for opioid dependence. While opioid-induced urinary retention and hesitancy are well known, urinary hesitancy in patients who receive buprenorphine treatment may go unrecognized and untreated. Objectives: The current study is a retrospective chart review of 104 charts of patients with a diagnosis of opioid dependence who received buprenorphine/naloxone treatment to examine the incidence of urinary hesitancy and identify the relationship of symptoms, if any, with the dose and duration of treatment and other patient and treatment factors. Results: Forty-five percent of patients reported no side effects, while 26% of the subjects reported urinary hesitancy symptoms at some point in treatment. Urinary symptoms were reported as early as one day and predominantly in the first 2 weeks after initiation of bup/nlx treatment. Conclusion: Urinary hesitancy occurs with buprenorphine is often under reported and may go untreated. It may lead to significant discomfort and could possibly interfere with patient compliance to buprenorphine treatment. In most cases the symptoms are mild and transient and can easily be treated with increased fluid intake and use of bethanechol, a cholinergic drug that has long been used for non-obstructive urinary hesitancy or retention, at low doses. Education of providers and patients regarding this early and tr

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