Calcification in Smaller and Larger Infrarenal Aneurysmatic Abdominal Aortas- Differences in Plaque Patterns -Christina Heilmaier1*, Theodoros Moysidis2, Dominik Weishaupt1 and Knut Kroger2
- *Corresponding Author:
- Christina Heilmaier
Department for Diagnostic Radiology
Stadtspital Triemli, 8063 Zurich, Switzerland
E-mail: [email protected]
Received Date: February 18, 2014; Accepted Date: April 18, 2014; Published Date: April 25, 2014
Citation: Heilmaier C, Moysidis T, Weishaupt D, Kroger K (2014) Calcification in Smaller and Larger Infrarenal Aneurysmatic Abdominal Aortas- Differences in Plaque Patterns. Angiol 2:129. doi:10.4172/2329-9495.1000129
Copyright: © 2014 Heilmaier C et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Introduction: Multi-detector computed tomography (MDCT) has established concerning analysis and quantification of vascular calcification in various vessels. We used MDCT for assessment of plaque architecture in smaller (<50 mm) and larger (≥50 mm) infrarenal abdominal aortic aneurysms (AAA).
Material & Methods: Study included 42 patients (<50 mm: n=20; ≥50 mm: n=22), who all underwent MDCT. Two readers performed quantitative and qualitative analysis, including calculation of calcium scores and measurement of plaque size and thickness. Calcium scores were calculated; t-tests were done to look for statistical differences between calcium scores and density ratios (=calcium score/aortic cross-sectional area). Cardiovascular risk factors were compared in patients with smaller and larger aneurysms.
Results: Calcium scores significantly rose with AAA diameter (mean value in smaller aneurysms: 488.8±375.7; in larger aneurysms: 1,687 ± 923; p< 0.001), but no considerable difference was seen in density ratios. Plaque architecture changed: while larger aneurysms mainly contained thin (1 or 2 mm) or intermediate (3 or 4 mm) plaques in circular or mixed grouped-circular arrangement, smaller aneurysms had thicker (≥5 mm) plaques that covered less than half of vessel circumference. On average, subjects had more than 2 cardiovascular risk factors with hypertension being the most frequent one. Number of cardiovascular risk factors present increased with AAA size, in larger aneurysms patients had 3.0 ± 1.2 risk factors compared to a mean of 1.8 ± 1.1 in smaller aneurysms (p=0.001).
Conclusion: Plaque pattern is different in smaller and larger AAA with thicker and more grouped plaques present in smaller AAA, which might have a stabilizing function on vessel wall.