Calcitonin and Parathyrin are Glucoregulating HormonesMoisa SS1* and Nozdrachev AD2
- Corresponding Author:
- Moisa SS
Federal State-Financed Establishment of Science
State Scientific Center of the Russian Federation
Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Russia
E-mail: [email protected]
Received date: December 13, 2013; Accepted date: February 25, 2014; Published date: March 03, 2014
Citation: Moisa SS, Nozdrachev AD (2014) Calcitonin and Parathyrin are Glucoregulating Hormones. J Mol Genet Med S1:024. doi: 10.4172/1747-0862.S1-024
Copyright: © 2014 Moisa SS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The comprehensive literature data and our findings about calcium-regulating hormones participant in the glucose metabolism is analyzed. It is showed calcitonin hyperglycemic effect and its mechanisms, established contra-insulin effect of calcitonin to insulin under the pre-receptor, cell level and liver. It is ascertained the impairment of glucose metabolism under calcitonin - hyperglycemia, insulin resistance and glucose intolerance. It is showed the data of combinative effect of calcitonin and calcium antagonists on glucose metabolism. It is discussed calcitonin diabetogenic effect and the role of calcium antagonists in the correction of hyperglycemia and tissue's insulin resistance. It was revealed the effect of parathyrin on glucose, occurring in decreasing the glucose level and increases glucose tolerance. It is concluded about participant of calcium-regulating hormones in the regulation of glucose metabolism.