alexa Cambodian Ministry of Health Takes Decisive Actions in the Fight against Substandard and Counterfeit Medicines | OMICS International | Abstract
ISSN: 2329-9088

Tropical Medicine & Surgery
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Research Article

Cambodian Ministry of Health Takes Decisive Actions in the Fight against Substandard and Counterfeit Medicines

Laura A Krech1*, Christi Lane-Barlow1, Lang Siv1, Souly Phanouvong1, Wei Elaine Yuan1, Bunkiet Heng2, Dararath Eav2, Sovannarith Tey3 and Lukas Roth1

1Promoting the Quality of Medicines Program, Global Health Impact Programs, United States Pharmacopeial Convention, USA

2Department of Drugs and Food, Ministry of Health of Cambodia, Cambodia

3National Health Product Quality Control Center, Ministry of Health of Cambodia, Cambodia

*Corresponding Author:
Laura A Krech
Promoting the Quality of Medicines Program
Global Health Impact Programs
United States Pharmacopeial Convention
Twinbrook Parkway 12601, Rockville
MD 20852-1790, USA
Tel: 240-221-4100
E-mail: [email protected]

Received Date: January 24, 2014; Accepted Date: February 28, 2014; Published Date: March 01, 2014

Citation: Krech LA, Barlow CL, Siv L, Phanouvong S, Yuan WE, et al. (2014) Cambodian Ministry of Health Takes Decisive Actions in the Fight Against Substandard and Counterfeit Medicines. Trop Med Surg 2:166. doi: 10.4172/2329-9088.1000166

Copyright: © 2014 Krech LA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Cambodia's Ministry of Health and the Department of Drugs and Food have been actively working to reduce the amount of poor quality medicines circulating in the pharmaceutical sector since fake mefloquine and artesunate were first found in 1998. From 2005-2012, legal private sector facilities and illegal outlets in twelve Cambodian provinces were targeted for routine surveillance of medicine quality through sample collection and testing of various anti-infective medicines, the majority of which were anti-malarials and anti-biotics. The Medicine Quality Monitoring program samples from the field were analyzed through a three level approach including field and advanced laboratory testing. 4,381 medicines were collected and tested from 2005-2012; 106 have failed quality testing resulting in an overall failure rate of 2.4%. 28 of the failed samples (26.4%) were counterfeit. The most commonly found counterfeit medicines were chloroquine, artesunate, mefloquine, ampicillin and penicillin. Cambodia has closed over 99% of illegal pharmacy outlets through the Inter-Ministerial Committee to Fight against Counterfeit & Substandard Medicines (IMC) by the end of November 2011. In the past, a lack of resources as well as coordination among the various ministries was identified as a major barrier in combating the presence of poor quality medicines. With financial support from USAID, PMI, and other donors, paired with the technical support from the U.S. Pharmacopeial Convention Promoting the Quality of Medicines program, the IMC developed an action plan to significantly reduce the number of substandard and counterfeit medicines. Based on the data shown, the plan has been successful in reducing the failure rates of samples collected in Cambodia from a high of 7.4% in 2006 to a low of 0.7% in 2011. Continued efforts to monitor and actively ensure the quality of medicines in Cambodia will be required to maintain these low rates; sustainability of these efforts is critical.

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