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ISSN: 1747-0862

Journal of Molecular and Genetic Medicine
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  • Short Communication   
  • J Mol Genet Med 2019, Vol 13(2): 422

Cancer: Stress and PAI-1

Lasierra-Cirujeda J1*, Aza-Pascual-Salcedo MJ2, Aza-Pascual-Salcedo MM3, Lasierra-Ibañez A4 and Lasala-Aza C5
1Department of Hematology, Logroño, La Rioja, Spain
2La Rioja Health Department, La Rioja, Spain
3Aragon Health Service, Zaragoza, Spain
4Faculty of Sciences, Department of Biochemistry, University of Navarra, Spain
5Faculty of Pharmacy, University of Valencia, Spain
*Corresponding Author : Dr. Lasierra-Cirujeda J, Hematologist, Department of Hematology, Gran Vía, N˚73, 1˚B, Logroño, La Rioja, Spain, Tel: 948 42 56 00, Email: [email protected]

Received Date: Feb 18, 2019 / Accepted Date: Apr 18, 2019 / Published Date: Apr 25, 2019

Abstract

Cancer is a group of diseases that are characterized by the development of abnormal cells, which divide almost without limit, develop, spread without control anywhere in the body, losing the cells their ability to disappear by an anti- apoptotic action, essential process for malignant transformation and tumor development. The onset and development of cancer is associated with multiple causes and predisposing factors such as stress and psychosocial factors PAI-1 is a gene regulated by stress and is paradoxicallyinteracted in close relation with uPA in the development of tumors.

Keywords: Cancer; Tumors; Genomic; Stress; Medicine

Citation: Lasierra-Cirujeda J, Aza-Pascual-Salcedo MJ, Aza-Pascual-Salcedo MM, Lasierra-Ibañez A, Lasala-Aza C (2019) Cancer: Stress and PAI-1. J Mol Genet Med 13:422.

Copyright: © 2019 Lasierra-Cirujeda J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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