Abstract

Coronary ischemic disease represents an important clinical problem worldwide. Each year millions of people (mostly women) with AP by visual analysis of biplane coronarography are found to have normal coronary arteries. However, as demonstrated from autoptic and ultrasound intravascular studies in vivo it would be more appropriate to say that coronarography did not detect obstructive or flow-limiting epicardial coronary artery disease. The pathology arises from a complex pathology in the microcoronary vessels and is usually called cardiac X syndrome. The paper describes the etiology and pathogenies of this pathology. Cardiac X syndrome is not a benign pathology because it induces angina pectoris and myocardial ischemia. Given the association between this pathology and consequent downstream morbidity, it seems logical to assess long-term cardiovascular outcomes by appropriate analysis. Drugs used in coronary artery disease are prescribed in cardiac X syndrome, but we lack data from double-blind randomized trials. Specific research to target interventions against this cardiac pathology CSX would be necessary.

Keywords: Cardiac Ischemia; cardiac X syndrome