Cardiovascular Diseases Associated with Pregnancy: Early Assessment Using Non-Invasive MicroRNA Profiling
Department of Health and Life Sciences, Faculty Research Centre in Applied Biological and Exercise Sciences, Coventry University, Coventry, UK
- Corresponding Author:
- Hardip Sandhu
Department of Health and Life Sciences
Faculty Research Centre in Applied Biological and Exercise Sciences
Coventry University, Coventry, UK
E-mail: [email protected]
Received date: October 29, 2015 Accepted date: December 11, 2015 Published date: December 19, 2015
Citation: Hardip Sandhu (2015) Cardiovascular Diseases Associated with Pregnancy: Early Assessment Using Non-Invasive MicroRNA Profiling. Clinics Mother Child Health 12:212. doi:10.4172/2090-7214.1000212
Copyright: © 2015 Sandhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
In some cases pregnancies are associated with severe cases of cardiovascular diseases (CVDs). The early detection and proper treatment of CVDs during maternity is detrimental to the health outcome and wellbeing of both mother and child. Unfortunately, both the detection rate and assessment of CVDs during pregnancies are unsatisfactory.
Currently, the messenger RNA (mRNA) regulators called microRNAs (miRNAs) are being extensively profiled for use as clinical CVDs biomarkers due to their specific tissue and disease expression signature profiles. The identification and development of reliable biomarkers for early clinical assessment of CVDs during pregnancy could allow the detection of sub-clinical cardiac injury risk in vulnerable pregnant patients before irreversible damage occurs. CVDs specific miRNA biomarkers could provide the clinicians with a valuable tool to allow prognosis of patients at risk of cardiovascular injury and the introduction of therapy and intervention in order to increase health outcome and survival rate of both the mother and child.