alexa Case study in drug discovery and development: When it doesn't go to plan Denufosol for the treatment of cystic fibrosis

Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Case Report

Case study in drug discovery and development: When it doesn't go to plan Denufosol for the treatment of cystic fibrosis

Christine Smith1 and W David Strain2*

1Novo Nordisk UK Ltd, UK.

2Diabetes and Vascular Medicine, University of Exeter Medical School, UK.

*Corresponding Author:
W David Strain
Diabetes and Vascular Medicine
University of Exeter Medical School
Barrack Road, Exeter EX2 5AX, UK
E-mail: [email protected]

Received date: 01 March 2016; Accepted date: 27 April 2016; Published date: 30 April 2016



In current healthcare provision there is an ever growing focus on acquisition cost of pharmacological interventions, and whether they represent value for money. It is often forgotten that for every “breakthrough” drug that makes it onto our formularies, approximately 1000 never get beyond phase 1 clinical trials. Even once this hurdle is passed, there are many more obstacles that stand in the way of a new medication ever being prescribed. The cost of the development of these failed medications is incorporated into the cost of every new product that is brought to market, therefore, every effort is made to ensure, once a product gets to the final stages of development it is used in the most appropriate population using the most appropriate outcomes in order to demonstrate its maximal efficiency.


Recommended Journals

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version