Catheter-Associated Venous Thromboembolism in Patients with Cystic FibrosisKamyar Afshar*, Ali Ahoui, Debbie S Benitez and Purush Rao A
Division of Pulmonary and Critical Care Medicine, University of Southern California, Keck School of Medicine, USA
- *Corresponding Author:
- Kamyar Afshar
Division of Pulmonary and Critical Care Medicine
University of Southern California
Keck School of Medicine 2020 Zonal Avenue
IRD 723, Los Angeles, CA 90033, USA
E-mail: [email protected]
Received date: January 27, 2013; Accepted date: March 26, 2013; Published date: March 29, 2013
Citation: Afshar K, Ahoui A, Benitez DS, Purush Rao A (2013) Catheter-Associated Venous Thromboembolism in Patients with Cystic Fibrosis. J Pulmon Resp Med 3:143. doi:10.4172/2161-105X.1000143
Copyright: © 2013 Afshar K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
We report a 45 year old male with right sided pleural mesothelioma who received neoadjuvant chemotherapy prior to a right extrapleural pneumonectomy followed by adjuvant chemotherapy. The patient became tumor free and remained in remission for 19 months following which he developed a lymphangitic spread over the contralateral lung. His diagnosis was confirmed by a bronchoscopic transbronchial biopsy of the left lung. The patient died from progressive respiratory failure over a period of three months. Such a relapse with an aggressive and fatal lymphangitic spread is rarely seen and reported in malignant pleural mesothelioma. Discussion and review of the literature are provided. Mesothelioma is still considered, worldwide, a rare cancer of the serosal membranes. It typically involves the pleural cavity but other reported sites include the peritoneum, pericardium and Tunica vaginalis of the testis. The usual progression of the mesothelioma is coalescence of multiple, small nodules into large masses that invade, entrap and destroy the affected organ by direct extension and invasion. We report an unusual case of relapsing mesothelioma, recurring in an aggressive and fatal form, after 19 months of remission.