alexa Cauda Equina Lymphoma - Case Report and Review of Liter
ISSN: 2165-7939

Journal of Spine
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Case Report

Cauda Equina Lymphoma - Case Report and Review of Literature

Pedro R Biasi1*, Luan Lucena1, Rafael Augusto Espanhol1, Timóteo Abrantes de Lacerda Almeida1, Matheus Pintos Brunet1, Wellington César de Souza1, Eduardo Felipe Martinelli Baldissera1, Laura Regyna Toffoli Roso2, Luídia Varrone Giacomini2, Fernando Luiz Giacomini3, Adroaldo Baseggio Mallmann4 and Charles André Carazzo4
1Neurosurgery Resident, Departamento of Neurosurgery, São Vicente de Paulo Hospital, Brazil
2Medical student of University of Passo Fundo, Brazil
3Neurophysiologist of São Vicente de Paulo Hospital, Brazil
4Neurosurgeon of Institute of Neurology and Neurosurgery of Passo Fundo, Brazil
Corresponding Author : Pedro Radalle Biasi
Av. Sete de Setembro, 65, ap 101 99010-121
Passo Fundo, RS, Brazil
Tel: +55 54 9617 2514
E-mail: [email protected] doctor.com
Received: October 28, 2015 Accepted: November 27, 2015 Published: November 30, 2015
Citation: Biasi PR, Lucena L, Espanhol RA, Almeida TAL, Brunet MP, et al. (2015) Cauda Equina Lymphoma – Case Report and Review of Literature. J Spine 4:267. doi:10.4172/2165-7939.1000267
Copyright: © 2015 Biasi PR, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

The Primary Central Nervous System Lymphoma is an uncommon disease and rarely affects the spinal cord. The authors present the case of a female patient, 67 year-old, with paresis of the left leg. Lumbosacral MRI depicts focal thickening of the cauda equina roots at L2 level, isointense on T1W and hyperintense on T2W with intense contrast enhancement. Immunohistochemistry analysis of a biopsied root confirmed the diagnosis of Diffuse Large B-cell Lymphoma. The PCNSL, generally represented by Large B-cells subtype, affects the spinal cord in less than one per cent of the cases and are generally associated with cytogenetic changes on BCL-6 gene. The appearance on MRI is not characteristic, evidencing the focal volumetric increase of the cauda equina roots, with intense contrast enhancement, being not possible to differentiate between lesions as schwannomas and meningiomas. For the diagnosis is necessary biopsy of the lesion and after intraoperative confirmation, resection should be suspended because it is not effective. The treatment is based on chemotherapy and radiotherapy, however, the prognosis is poor.

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