alexa Cavum Septi Pellucidi as a Marker of the Neuropsychiatric Diseases: A Pointer or Mislead? A Cadaveric-Clinical Observation | OMICS International
ISSN: 2157-7145

Journal of Forensic Research
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Research Article

Cavum Septi Pellucidi as a Marker of the Neuropsychiatric Diseases: A Pointer or Mislead? A Cadaveric-Clinical Observation

Branislav Filipovic1,2*, Nikola Ilankovic1,3, Ana Starcevic1,2, Branka Filipovic1,4, Lazar Stijak1,2, Laslo Puskas1,2 and Tatjana Atanasijevic1,5

1University of Belgrade, Faculty of Medicine, Belgrade, Serbia

2Institute of Anatomy “Niko Miljanic”, Belgrade, Serbia

3Institute of Psychiatry, Clinical Center of Serbia, Belgrade, Serbia

4Clinical and Hospital Center Bezanijska Kosa, Belgrade, Serbia

5Institute for Forensic Medicine, Belgrade, Serbia

*Corresponding Author:
Branislav Filipovic
Institute of Anatomy “Niko Miljanic”
4/2 Dr. Subotica Starijeg
11000 Belgrade, Serbia
Tel: +381112684259
E-mail: [email protected]

Received date: August 28, 2013; Accepted date: December 05, 2013; Published date: December 12, 2013

Citation: Filipovic B, Ilankovic N, Starcevic A, Filipovic B, Stijak L, et al. (2013) Cavum Septi Pellucidi as a Marker of the Neuropsychiatric Diseases: A Pointer or Mislead? A Cadaveric–Clinical Observation. J Forensic Res 5:208. doi: 10.4172/2157-7145.1000208

Copyright: © 2013 Filipovic B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Cavum Septi pellucid (CSP), a cavity between the laminae of the septum pellucidum, for a longer period has been reported as an anomaly of the brain midline, associated with neuropsychiatric diseases, mostly schizophrenia, but also posttraumatic stress disorder, De la Tourette disease, and persons who survived a repeated a serious head trauma, boxers on the first place. Our investigation has been performed on 479 unfixed frozen brains, of the autopsied individuals of both genders, and MRI scans of 250 examinees, out of which 110 had neuropsychiatric illness. In our sample, the prevalence of CSP was 22.96% among the autopsied individuals and 9.2% in examinees who underwent MRI scan. The cause of the death among schizophrenia suffering persons was suicide (18 out of 25 patients). Obviously, CSP is more frequently associated with neuropsychiatric diseases, but a dilemma still exists, did we make a bias in brain suitability for the examination or we did the same mistake in observing clinical cases. A large CSP, though, is an almost certain sign for an underlying neuropsychiatric impairment, especially schizophrenia. The CSP among alcoholics and persons with the priory sustained head blows is probably of the same cause and represents an aftermath of the diffuse axonal injuries, i.e. brain trauma.

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