alexa CDKs: Much More Than Just the Control of Cell Cycle Pro
ISSN: 2157-7013

Journal of Cell Science & Therapy
Open Access

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CDKs: Much More Than Just the Control of Cell Cycle Progression

Felicia Hanzu and Xavier Escoté*

Endocrine Disorders Research Group, Hospital Clínic & IDIBAPS, Barcelona, Spain

*Corresponding Author:
Xavier Escoté
Endocrine Disorders Research Group
Hospital Clínic & IDIBAPS, C/Rosselló
149-153, 5th floor, 08036 Barcelona, Spain
Tel: 3493227570
E-mail: [email protected]

Received Date: June 13, 2014; Accepted Date: July 29, 2014; Published Date: July 31, 2014

Citation: Hanzu F, Escoté X (2014) CDKs: Much More Than Just the Control of Cell Cycle Progression. J Cell Sci Ther 5:170. doi: 10.4172/2157-7013.1000170

Copyright: © 2014 Hanzu F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Lee and colleagues have shown that CDK4 plays a central role in glucose homeostasis. Insulin activates cyclin D1–CDK4, leading to a decrease in circulating glucose as a consequence of the down-regulation of main genes involved in liver gluconeogenesis.

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