alexa Central Giant Cell Granuloma Resistant to Calcitonin Nasal Spray: A Case Report | OMICS International | Abstract
ISSN: 2161-1173

Reconstructive Surgery & Anaplastology
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Case Report

Central Giant Cell Granuloma Resistant to Calcitonin Nasal Spray: A Case Report

Lucia Gerzanic1*, Günter Schultes1, Hans Kärcher1 and Doris Zebedin2

1Department of Oral and Maxillofacial Surgery, Medical University of Graz, Auenbruggerplatz, Austria

2Department of Radiology, Medical University of Graz, Auenbruggerplatz, Austria

*Corresponding Author:
Lucia Gerzanic
Department of Oral and Maxillofacial Surgery
Medical University of Graz
Auenbruggerplatz 12, A-8036 Graz, Austria
Tel: 00436641124229
Fax: 0043/316/385/351
E-mail: [email protected]

Received Date: July 19, 2013; Accepted Date: September 14, 2013; Published Date: September 18, 2013

Citation: Gerzanic L, Schultes G, Kärcher H, Zebedin D (2013) Central Giant Cell Granuloma Resistant to Calcitonin Nasal Spray: A Case Report. Anaplastology 2:119. doi:10.4172/2161-1173.1000119

Copyright: © 2013 Al-Sukhun J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Purpose: We describe successful treatment of a recurrent central giant cell granuloma (CGCG). This is a rare benign intraosseous lesion that occurs before age 30 and can quickly recur as a painless lesion of the mandible.Because of its aggressive growth and tendency to progress as well as its morphological similarity to a giant cell tumour, it justifies radical surgery.
Patients and methods: A female patient aged 18 years presented with a CGCG lesion in the mandible that recurred despite standard treatment with calcitonin nasal spray after enucleation of the initial lesion.
Results: The recurrence in the mandible required radical surgery and reconstruction with a microvascular iliac bone flap; there was no injury to cranial nerves and facial appearance was normal.
Conclusion: Radical surgical treatment of CGCG recurrence is the best option when calcitonin nasal spray fails to prevent recurrence.


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