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ISSN: 2155-6156

Journal of Diabetes & Metabolism
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Research Article

Characteristics of Ketosis-onset Diabetes in Tunisian Population

Melika Chihaoui*, Faouzi Kanoun, Nadia Tabassi, Bochra Ftouhi, Meriem Yazidi, Faiza Lamine and Hedia Slimane

Department of Diabetology-Endocrinology, University Hospital La Rabta, Tunis, Tunisia

*Corresponding Author:
Melika Chihaoui
Department of Diabetology-Endocrinology
University Hospital La Rabta
Tunis Endocrinology Jabbari, Tunis, Tunisia
E-mail: [email protected]

Received date: October 29, 2011; Accepted date: Feberuary 20, 2012; Published date: Feberuary 25, 2012

Citation: Chihaoui M, anoun F, Tabassi N, Ftouhi B, Yazidi M, et al. (2012) Characteristics of Ketosis-onset Diabetes in Tunisian Population. J Diabetes Metab 3:175. doi:10.4172/2155-6156.1000175

Copyright: © 2012 Chihaoui M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Different types of diabetes can be presented by a ketosis (DK) or ketoacidosis (DKA). The objectives of this study were to analyze the characteristics of patients with newly diagnosed diabetes revealed by DK or DKA and discuss the different types of diabetes particularly ketone prone type 2 diabetes.

Subjects and methods: Retrospective study including 288 patients with new ketosis onset diabetes; 178 men, mean age: 35.5 years. We analyzed clinical, biological, therapeutic and subsequent clinical course data. Diabetes was classified according to clinical, biological and follow-up data.

Results: It was a DKA in 39 cases (13.5 %). Patients were classified as type 1 in 62.2% of cases and ketosis type 2 diabetes in 34.7 % of cases. As compared to type 1 diabetes, ketosis type 2 diabetes patients had a more advanced age, higher body mass index and waist circumference, and less frequent DKA. After the acute episode, 60% of ketosis type 2 diabetes was treated with insulin and half of them had associated metformin. After a mean follow-up of 2.4 years, 52% of ketosis type 2 diabetes patients were treated with oral hypoglycemic agents.

Conclusion: Ketosis type 2 diabetes is a relatively new entity accounting for about one third of all new cases of DK or DKA in our population.


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