Characterization and Identification of the Components Extracted from 28 Lichens in Tunisia by High Performance Thin-Layer Chromatography (HPTLC), Morphologic Determination of the Species and Study of the Antibiotic Effects of Usnic Acid
Karima Tabbabi* and Tijani Karmous
Laboratory of Natural Substances, Faculty of Sciences of Bizerte, University of Carthage, Bizerte, Tunisia
- *Corresponding Author:
- Karima T
Laboratory of Natural Substances
Faculty of Sciences of Bizerte
University of Carthage
Zarzouna 7021, Bizerte, Tunisia
Received date: May 02, 2016; Accepted date: May 31, 2016; Published date: June 03, 2016
Citation: Tabbabi K, Karmous T (2016) Characterization and Identification of the Components Extracted from 28 Lichens in Tunisia by High Performance Thin-Layer Chromatography (HPTLC), Morphologic Determination of the Species and Study of the Antibiotic Effects of Usnic Acid. Med Aromat Plants 5:253. doi:10.4172/2167-0412.1000253
Copyright: © 2016 Tabbabi K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This aim of this work is to study the isolation of usnic acid found in many lichen species and the evaluation of its antibacterial activity. The study began with a morphological determination of lichens harvested in Tunisia. The corresponding analysis identified 28 species belonging to the following families: Xanthoria, Parmelia, Caloplaca, Ramalina, Diploschistes, Usnea. A chromatographic study of the chemical composition of these lichens highlighted the presence of many compounds belonging to various chemical categories: depsides and depsidones, xanthones, anthraquinones, dibenzofurans, etc. Special attention was given to the components of this last category and particularly to usnic acid which is therapeutically very interesting. This component plays a very important role in fighting the bacteria responsible for numerous urinary and pulmonary infections and also in fighting viruses responsible for certain tumors. Antibacterial activity tests showed that the Staphylococcus aureus and Enterococci strains have certain sensitivity to usnic acid extracted from the Usnea hirta lichen. Given that various fields, and especially medicine, are currently showing considerable interest in vegetable extracts, this study will be continued in the future with the aim to isolate other components with efficient therapeutic effects.