alexa Characterization of Cardiac Troponin I Raman Signature
ISSN: 2329-6836

Natural Products Chemistry & Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Characterization of Cardiac Troponin I Raman Signature in Bovine Serum Albumin and Human Blood Serum for the Potential Diagnosis of Myocardial Infarction

Sara Moghaddamjoo1*, Amir Pasha Tashakor1, Sahba Talebi Fard1, Yashar Tashakkor A2,3, Ezra Kwok1, Yueh Alison Li5, Najme Tavassoli4, Glen F Tibbits5, Grant Ed4 and Andrew Rawicz3
1Biomedical Engineering Program, Faculty of Applied Science, University of British Columbia, Vancouver, British Columbia, Canada
2Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
3Division of Biomedical Engineering, School of Engineering Science, Simon Fraser University, Vancouver, British Columbia, Canada
4Department of Chemistry, Faculty of Science, University of British Columbia, Vancouver, British Columbia, Canada
5Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Vancouver, British Columbia, Canada
Corresponding Author : Sara Moghaddamjoo
Biomedical Engineering Program
Faculty of Applied Science, University of British Columbia
Vancouver, British Columbia, Canada
E-mail: [email protected]
Received: December 12, 2015; Accepted: December 19, 2015; Published: December 22, 2015
Citation: Moghaddamjoo S, Tashakor AP, Fard ST, Tashakkor AY, Kwok E, et al. (2015) Characterization of Cardiac Troponin I Raman Signature in Bovine Serum Albumin and Human Blood Serum for the Potential Diagnosis of Myocardial Infarction. Nat Prod Chem Res 4:200. doi:10.4172/2329-6836.1000200
Copyright: © 2015 Moghaddamjoo S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Related article at Pubmed, Scholar Google
 

Abstract

Cardiac troponin I is one of the most specific and widely used biomarkers of myocardial infarction. Prompt recognition of elevated troponin concentrations in the blood is essential to the diagnosis and management of acute coronary syndrome (ACS). Raman spectroscopy allows for detection of the unique cTnI Raman signature based on quantitative measurement of wavelength and intensity of in elastically scattered light from molecules. For the first time in the literature, we have successfully characterized and verified the unique Raman signature of mouse cardiac troponin I protein in Bovine Serum Albumin and Human Blood Serum. Our findings potentiate technological advancement towards point-of-care testing measurement of cardiac biomarkers, which can be employed, potentially more rapid than conventional ELISA assays, in the outpatient setting and emergency departments for routine detection of cardiac troponin I elevation from patients suspected of suffering from acute coronary artery syndrome

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords