alexa Childhood Chronic Inflammatory Demyelinating Polyneurop
ISSN: 2168-975X

Brain Disorders & Therapy
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Case Report

Childhood Chronic Inflammatory Demyelinating Polyneuropathy – A Report of Two Cases

Shobhana Sivathanu and Sowmya Sampath*
Department of Paediatrics, ESIC Medical College & PGIMSR, K.K Nagar, Chennai, India
Corresponding Author : Sowmya Sampath
Professor and Head
Department of Paediatrics
ESIC Medical College & PGIMSR
K.K Nagar, Chennai, India
Tel: 91 44 24748959
E-mail: [email protected]
Received November 18, 2014; Accepted November 30, 2014; Published December 15, 2014
Citation: Sivathanu S, Sampath S (2015) Childhood Chronic Inflammatory Demyelinating Polyneuropathy – A Report of Two Cases. Brain Disord Ther 4:155. doi:10.4172/2168-975X.1000155
Copyright: © 2015 Sivathanu S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disorder characterised by demyelination of nerve roots and nerves. CIDP is less common in children but it has a favourable outcome as compared to adults. The course may be monophasic and progressive or characterised by recurrent relapses. The characteristic clinical presentation is with both proximal and distal muscle weakness with areflexia. Steroids, immunoglobulin and plasmapheresis are the mainstay of treatment. Of all these modalities, steroids are more likely to induce long lasting remission. In this article, we are reporting two children with CIDP – one with the monophasic and the other with the relapsing course, with a view to highlight the differences in presentation and the fact that it remains an under diagnosed condition due to its protean manifestations.

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