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ISSN: 1747-0862

Journal of Molecular and Genetic Medicine
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Review Article

Chitosan: A Promising Biopolymer in Drug Delivery Applications

Chinmayee Saikia, Pankaj Gogoi and Tarun K Maji*

Department of Chemical Sciences, Tezpur University, Tezpur, Assam, India

Corresponding Author:
Tarun K Maji
Department of Chemical Sciences
Tezpur University, Tezpur, Assam, India
Tel: +91 3712 275053
Fax: +91 3712 267005
Email: [email protected]

Received date: August 19, 2015 Accepted date: October 06, 2015 Published date: October 13, 2015

Citation:Saikia C, Gogoi P, Maji TK (2015) Chitosan: A Promising Biopolymer in Drug Delivery Applications. J Mol Genet Med S4:006. doi:10.4172/1747-0862.S4-006

Copyright: © 2015 Saikia C, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Drug delivery system with controlled release technology has emerged as a powerful tool for the treatment of various diseases. The therapeutic index of the active agent can be enhanced by increasing its stability, solubility and bioavailability, along with specific site delivery. Polymers have been playing an integral role as carrier in formulating an efficient drug delivery system by their stability, drug loading capacity and tunable properties. ‘Chitosan’ the natural cationic polymer derived from chitin has received growing attention mainly due to their biodegradable, biocompatible, non-toxic, mucoadhesive and ability to target specific delivery properties. Chitosan has itself many medicinal properties like antimicrobial, antioxidant, low immunogenicity etc. which enhance its potential in different biomedical applications. The various techniques for preparation of chitosan micro/nano particles are discussed in this review. Various types of chitosan based drug delivery systems are surveyed to elucidate its role in different biomedical applications.

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