alexa Cholangiocarcinoma: A Single-center Western Experience | OMICS International| Abstract

ISSN: 2168-9784

Journal of Medical Diagnostic Methods

  • Research Article   
  • J Med Diagn Meth 2018, Vol 7(2): 270
  • DOI: 10.4172/2168-9784.1000270

Cholangiocarcinoma: A Single-center Western Experience

Giulio Di Mare1, Daniele Marrelli1, Costantino Voglino1, Francesco Ferrara1,2*, Riccardo Piagnerelli1, Mario Marini1 and Franco Roviello1
1Department of Medicine, Surgery and Neurosciences, University of Siena, Italy
2Department of Surgery, San Carlo Borromeo Hospital, Milan, Italy
*Corresponding Author : Francesco Ferrara, Department of Medicine, Surgery and Neurosciences, University of Siena, San Carlo Borromeo Hospital, Milan, Italy, Tel: +390240222183, Email: [email protected]

Received Date: Apr 10, 2018 / Accepted Date: May 14, 2018 / Published Date: May 22, 2018

Abstract

Background: The purpose of this study was to summarize the surgical management and to evaluate survival rate and clinical outcome of cholangiocarcinoma, in patients hospitalized in our Unit of Oncology and General Surgery.
Methods: This is a retrospective analysis of 76 consecutive patients with diagnosis of cholangiocarcinoma. The surgical procedure was selected based on the origin of the neoplasia. Tumor stage was defined according to the pathological tumour-node-metastasis classification (TNM 7th edtn, 2010). After resection, all patients underwent regular follow-up.
Results: During the study period, 58 patients underwent explorative laparotomy. Forty-six patients were submitted to respective surgery with curative intent. A curative resection (R0) was achieved in 42/46 resected patients. The overall median survival time was 14.2 months, with 1, 3 and 5 year survival rates of 53.6%, 37.7%, and 19.6%, respectively. The survival rates, for the patients underwent R0 resection, was respectively 69%, 47.8% and 32.6% at 1, 3 and 5 years, with median survival time of 20.1 months.
Conclusions: Our experience confirms the main role of R0 surgery in the curative treatment of cholangiocarcinoma.

Keywords: Cholangiocarcinoma; Hepato-biliary cancer; Surgery

Citation: Di Mare G, Marrelli D, Voglino C, Ferrara F, Piagnerelli R, et al. (2018) Cholangiocarcinoma: A Single-center Western Experience. J Med Diagn Meth 7: 270. Doi: 10.4172/2168-9784.1000270

Copyright: © 2018 Di Mare G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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