alexa Circulating Soluble Corin: A New Biomarker or Risk Factor for Age-Related Disorders | OMICS International | Abstract
ISSN: 2167-7182

Journal of Gerontology & Geriatric Research
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Commentary

Circulating Soluble Corin: A New Biomarker or Risk Factor for Age-Related Disorders

Shi Chen1 and Hao Peng2*
1School of Nursing, Medical College of Soochow University, Suzhou, China
2Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China
Corresponding Author : Peng H
Department of Epidemiology, School of Public Health
Medical College of Soochow University
199 Ren-ai Road, Industrial Park District
Suzhou, 215123, China
Tel: 086-512-6588-0078
E-mail: [email protected] com
Received: April 17, 2015; Accepted: June 15, 2015; Published: June 18, 2015
Citation: Chen S, Peng H (2015) Circulating Soluble Corin: A New Biomarker or Risk Factor for Age-Related Disorders. J Gerontol Geriat Res 4:222. doi:10.4172/2167-7182.1000222
Copyright: © 2015 Chen S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Natriuretic peptides have been associated with age-related disorders including cardiovascular disease and its metabolic risk factors such as hypertension, diabetes, obesity, and dyslipidemia. Recently, human corin, a type II transmembrane serine protease highly expressed in the heart, was found to play a physiological role in activation of natriuretic peptides. As a physiological activator of natriuretic peptides, corin might be associated with agerelated disorders.

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