Journal of Nanomedicine & Biotherapeutic Discovery
Open Access

Abstract

Salivary Antioxidant Power of Passive Smokers

Azadbakht M, Sariri R, Soltani FM, Ghafoori H, Aghamaali MR and Erfani Karimzadeh Toosi A

Introduction: Cigarette smoke has been proven to be injurious to both oral cavity and internal body environment. Passive smokers could also suffer from smoke. Saliva, the first biological fluid which encounters cigarette smoke, contains antioxidant defense system to reduce the toxic effects of cigarette smoke. Objectives: The aim was investigating salivary

antioxidants

of passive smokers as compared to non-smokers. Method: Un-stimulated whole saliva samples, obtained from passive smokers and non-smokers, were centrifuged and stored at -70°C. The antioxidant power was then measure using various methods. Results: No statistically significant difference in antioxidant capacity, total phenol, and radical scavenging activity of saliva between studied groups was found. However, concentration of uric acid, the important antioxidant of saliva, was decreased dramatically in passive smokers. Conclusions: It was suggested that measurement of antioxidants in salivary fluid could be a useful noninvasive method to investigate abnormalities related to oral cavity and

gastrointestinal tract.