alexa Clinical and Epidemiological Differences between Women and Men with HIV Infection in Mexico
ISSN 2155-6113

Journal of AIDS & Clinical Research
Open Access

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Research Article

Clinical and Epidemiological Differences between Women and Men with HIV Infection in Mexico

Mata-Marín José Antonio1, Chaparro-Sánchez Alberto1*, Hernández-López Juan Carlos2, Huerta-García Gloria3, Domínguez-Hermosillo Juan Carlos1 and Cruz-Domínguez Pilar2

1Infectious Diseases Department, Hospital de Infectología, “La Raza” National Medical Center, IMSS, Mexico

2Internal Medicine Department, Hospital de Especialidades, “La Raza” National Medical Center, IMSS, Mexico

3Pediatric Infectious Diseases Department, Hospital de Pediatría, “Siglo XXI” National Medical Center, IMSS, Mexico

*Corresponding Author:
Dr. Alberto Chaparro Sánchez
Instituto Mexicano del Seguro Social, Hospital de Infectología
Centro Médico Nacional “La Raza”
Serisy Jacarandas s/n colonia la Raza
Del. Azcapotzalco, México, DF, CP. 02990
Tel: 57825900; ext 23924
E-mail: [email protected]

Received date: December 03, 2015; Accepted date: February 24, 2016; Published date: March 04, 2016

Citation: Antonio MMJ, Alberto CS, Carlos HLJ, Gloria HG, Carlos DHJ, et al. (2016) Clinical and Epidemiological Differences between Women and Men with HIV Infection in Mexico. J AIDS Clin Res 7:551. doi:10.4172/2155-6113.1000551

Copyright: © 2016 Antonio MMJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Objective: To evaluate the differences in gender for epidemiological, immunological, and virological outcomes at baseline, and response after 24 weeks of antiretroviral therapy in patients treated at the Hospital de Infectología “La Raza” National Medical Center.

Methods: We reviewed the medical records from March to August 2014 of outpatients who started treatment in our clinic; 65 women and 138 men in a cross-sectional study. Descriptive results are summarized using the median and 25th-75th interquartile range (IQR). Baseline differences were tested using Fisher’s exact test and the Chi-squared test. Analyses of continuous variables were performed using the Mann-Whitney U test.

Results: Similar proportions of women and men were found in the following factors: living in metropolitan area, age <40 years, economic household income source, baseline CD4+ ≤ 200 cells/μL, CD4+ ≥200 cells/μL at week 24, HIV-1 RNA ≤50 copies/mL at week 24, and opportunistic infections. Women are more usually married than men (75% vs. 10%, p<0.001); men with a higher academic degree (34% vs. 9%, p<0.001); men with an onset of sexual activity <20 years (85% vs. 79%, p=0.26); women with ≤4 sexual partners (92.3% vs. 26.3%, p<0.001); women with children (92% vs. 20%, p<0.001); men with some addiction (29% vs. 10%, p=0.04); women with baseline HIV-1 RNA viral load >100,000 copies/mL (37% vs. 54%, p=0.020); and women with virological treatment failure (10.8% vs. 2.2%, p=0.008).

Conclusion: Compared with men, mostly women showed adverse epidemiological and clinical conditions that made women more vulnerable to transmission through heterosexual activity, and more frequently present virological failure.

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