Journal of Clinical Chemistry and Laboratory Medicine
Open Access

Abstract

Clinical Application of Metabolomics in Pancreatic Diseases: A Mini-Review

Wang Gu, Zhong Tong and Tong Zhong

Metabolomics is an important part of system biology and an emerging discipline developed after genomics and proteomics. Metabolomics is a powerful new analytical method to describe the metabolomics of cells, tissue or biological body fluids. Metabolomics can provide the detailed information of the organism metabolic changes of these metabolites form represents the metabolic process occurs in the cell, such as anabolic catabolism metabolic distributed and heterogeneous natural absorption metabolism detoxification metabolism of biomass energy utilization metabolism, so some disease specificity of change can be found through metabonomics test, for the early identification of disease and the difference between benign and malignant state provide a new source of biomarkers. Metabolomics has a wide application potential in pancreatic diseases, including early detection, diagnosis and identification of pancreatic diseases, as well as prediction of drug effects and pharmacodynamics markers, but there are few studies on metabolomics in pancreatic diseases. This article reviews the application of metabolomics in the diagnosis, prognosis, treatment and evaluation of pancreatic diseases.