alexa Clinical Characteristics and Diagnostic Delay in Spinal Tuberculosis Patients in The Netherlands | OMICS International | Abstract
ISSN: 2161-1068

Mycobacterial Diseases
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Research Article

Clinical Characteristics and Diagnostic Delay in Spinal Tuberculosis Patients in The Netherlands

Ijdema D1#, Magis-Escurra C2#*, Horsting PP3, Erkens C4, Aarnoutse R5 and Boeree MJ2

1Radboud University, Faculty of Medicine, Nijmegen, The Netherlands

2Radboud University Medical Centre, University Centre for Chronic Diseases, Dekkerswald, Department of Pulmonary diseases, Groesbeek, The Netherlands

3Sint Maartenskliniek, Department of Orthopedic Surgery, Nijmegen, The Netherlands

4KNCV Tuberculosis Foundation, The Hague, The Netherlands

5Radboud University Medical Centre, Department of clinical Pharmacy, Nijmegen, The Netherlands

#Shared first authorship

Corresponding Author:
Cecile Magis-Escurra
Radboud University Medical Centre
University Centre for Chronic Diseases
Dekkerswald, Department of Pulmonary
diseases, Groesbeek, The Netherlands
Tel: +31246859293
E-mail: [email protected]

Received Date: June 5, 2015 Accepted Date: July 7, 2015 Published Date: July 15, 2015

Citation: Ijdema D, Magis-Escurra C, Horsting PP, Erkens C, Aarnoutse R, et al. (2015) Clinical Characteristics and Diagnostic Delay in Spinal Tuberculosis Patients in The Netherlands. Mycobact Dis 5:187. doi:10.4172/2161-1068.1000187

Copyright: © 2015 Ijdema I, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Introduction: With declining TB incidences diagnostic delays, especially in extra-pulmonary TB, may increase. We describe the patient and clinical characteristics of patients with spinal TB and assessed the course of diagnostic delays of spinal TB from 2000-2011 in The Netherlands.

Methods: Data from the Netherlands Tuberculosis Registry were studied, completed with basic demographic data and data considering patients-, doctors- and total diagnostic delay retrieved from the patient records at the public municipal health services.

Results: A total of 274 cases were studied. Median diagnostic delay was five months and stable during this period. Sex and age groups were associated with significant differences in diagnostic delay (male 4.5 vs female 5.5 months), and 4.5-5 months in the youngest age group and persons>65 years but 5.75 months in patients aged 35-64 years. No difference was observed between origin of patients, patients presenting with TB risk factors or with neurological symptoms. Typical TB symptoms at presentation lead, surprisingly, to significantly increased doctors’ delay (typical symptoms 4.0 vs no typical symptoms 2.0 months, p=0.05).

Conclusion: Considering spinal TB diagnosis and act expeditious is necessary to limit the time to diagnosis in spinal TB. Refresher courses should be offered both to family physicians and clinical specialists in The Netherlands


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