alexa Clinical Evaluation of Ultrasound-Guided Thoracic Paravertebral Block (TPVB) Effect on Postoperative Analgesia in Patients with Breast Cancer after Radical Mastectomy
ISSN: 2167-1079

Primary Healthcare: Open Access
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Research Article

Clinical Evaluation of Ultrasound-Guided Thoracic Paravertebral Block (TPVB) Effect on Postoperative Analgesia in Patients with Breast Cancer after Radical Mastectomy

Jin Xu#, Yilu Zhou#, Yinglin Wang and Hao Zhang*

Department of Anesthesiology, Shanghai East Hospital, Tongji University School of Medicine, China

#Authors contributed equally

Corresponding Author:
Hao Zhang
Department of Anesthesiology
Shanghai East Hospital
Tongji University School of Medicine, China
Tel: 15000790452
E-mail: [email protected]

Received date: September 13, 2016; Accepted date: November 25, 2016; Published date: December 02, 2016

Citation: Xu J, Zhou Y, Wang Y, Zhang H (2016) Clinical Evaluation of Ultrasound- Guided Thoracic Paravertebral Block (TPVB) Effect on Postoperative Analgesia in Patients with Breast Cancer after Radical Mastectomy. Primary Health Care 6:247. doi:10.4172/2167-1079.1000247

Copyright: © 2016 Xu J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Objective: To evaluate an ultrasound-guided thoracic paravertebral block (TPVB) on postoperative analgesia in breast cancer patients after radical mastectomy. Methods: Sixty female breast cancer patients underwent radical mastectomy and were randomly divided into the TPVB group and the control group. With 30 cases in each, Patients in the TPVB group received a 20 ml of 0.5% ropivacaine under ultrasound guidance and those in the control group received the same volume normal saline. All patients received patient-controlled intravenous analgesia. Postoperative pain value, were recorded at 1st, 4th, 8th, 12th, 24th and 48th hour at rest and on movement using the Visual Analogue Scale (VAS). The consumption of sufentanil and adverse reactions were also evaluated. The incidence of chronic pain was investigated with telephone interview after 3 month and 6 month, postoperatively. Results: Postoperatively at 1st, 4th, 8th, 12th, 24th hour patients in control group had significantly higher VAS values both at rest and on movement than those in the group treated with a thoracic paravertebral block (P<0.05). The opioid consumption in TPVB group were lower than that in control group (P<0.01).The incidences of nausea, vomit and chronic pain in TPVB group were significantly lower than those in control group. Conclusion: Ultrasound-guided paravertebral block can provide good postoperative analgesia effects for breast cancer patients after radical mastectomy. It reduces the opioid consumption, adverse reactions, and incidence of chronic pain. Decreases postoperative pain values and the need for analgesics during the postoperative 24 h, has obvious advantages in chronic pain relief.


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