alexa Clinical Study of Customized Selected Aspherical Intraocular Lens Implants
ISSN: 2155-9570

Journal of Clinical & Experimental Ophthalmology
Open Access

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Research Article

Clinical Study of Customized Selected Aspherical Intraocular Lens Implants

Liexi Jia, Zhaohui Li and Yifei Huang*
Department of Ophthalmology, Chinese PLA General Hospital, 100853, Beijing, China
Corresponding Author : Yifei Huang
Fuxing Road 28
Department of Ophthalmology
Chinese PLA General Hospital
100853, Beijing, China
Tel: +861066875523
Fax: +861068286682
E-mail: [email protected]
Received July 07, 2012; Accepted August 09, 2012; Published August 13, 2012
Citation: Jia L, Li Z, Huang Y (2012) Clinical Study of Customized Selected Aspherical Intraocular Lens Implants. J Clin Exp Ophthalmol 3:240. doi:10.4172/2155-9570.1000240
Copyright: © 2012 Jia L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Aims: To compare if there is an improvement in visual functions with age-related cataracts between patients
receiving customized selected aspherical intraocular lens (IOL) implants and patients randomly assigned lenses.
Methods: Ninety-four patients (94 eyes) with age-related cataracts were placed in experimental group or a
group receiving randomly assigned (RA) lenses. All patients were undergone Pentacam corneal spherical aberration
measurement before surgery; The targeted range for residual total spherical aberration after surgery was set to 0-0.3
μm in experimental group. Patients with a corneal spherical aberration ≤ 0.3 μm were implanted with a zero-spherical
aberration advanced optics (AO) aspherical intraocular lens and patients with an aberration 0.3 μm received a Tecnis
ZA9003 aspherical lens. RA patients were randomly implanted with an AO lens or a Tecnis ZA9003 lens. Three months
after surgery total spherical aberration, photopic/mesopic contrast sensitivities, photopic/mesopic with glare contrast
sensitivities, and LogMAR vision were measured.
Results: Statistical analysis on LogMAR vision showed no significant difference between two groups (P = 0.308).
The post-surgical total spherical aberration was 0.120 ± 0.097 μm and 0.158 ± 0.152 μm in the experimental and RA
groups, respectively (P = 0.08). The mesopic contrast sensitivities at spatial frequencies of 6, 12 and 18 c/d in the
experimental group were significantly higher than of the RA group (P = 0.00; P = 0.04; P = 0.01). The mesopic with
glare contrast sensitivity in the RA group at a spatial frequency of 18 c/d was also significantly higher vs. the RA group
(P = 0.02).
Conclusion: Pre-surgical corneal spherical aberration measurement in cataract patients followed by customized
selection of aspherical intraocular lens implants improved mesopic contrast sensitivities and mesopic with glare contrast
sensitivities at high spatial frequencies, and thus is a superior strategy compared to the random selection of aspherical
intraocular lens implants.

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